Flutamide
What is Flutamide?
Flutamide is an antiandrogen. It works in the body to prevent the actions of androgens (male hormones). Flutamide is used in the treatment of prostate cancer. Flutamide may also be used for purposes other than those listed in this medication guide.
What is the most important information I should know about Flutamide?
In rare cases, Flutamide has caused severe liver damage resulting in death or hospitalization. Notify your doctor immediately if you develop nausea, vomiting, abdominal pain, unusual fatigue, loss of appetite, “flu-like” symptoms, yellow skin or eyes, itching, clay-colored stools, or dark urine. These symptoms may be early signs of liver damage. Your doctor will need to monitor your liver function with blood tests before starting treatment with Flutamide, every month for the first 4 months of treatment, and periodically thereafter. Do not stop taking this medication without first talking to your doctor.
Usual Adult Dose for Hirsutism:
Data has been reported in which 250 mg of Flutamide 2 to 3 times daily in combination with oral contraceptives has been used in the treatment of female patients with hirsutism. However, FDA approved package labeling states that Flutamide has no indication for women, and should not be used in this population, particularly for non-serious or non-life threatening conditions.
What other drugs will affect Flutamide?
Before taking Flutamide, tell your doctor if you are taking warfarin (Coumadin). Flutamide may interact with warfarin, and the interaction could lead to bleeding. Drugs other than those listed here may also interact with Flutamide. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
Where can I get more information?
- Your pharmacist has additional information about Flutamide written for health professionals that you may read.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with other, and use this medication only for the indication prescribed.
- Every effort has been made to ensure that the information provided by Cerner Multum, Inc. (‘Multum’) is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum’s drug information does not endorse drugs, diagnose patients or recommend therapy. Multum’s drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Why is Flutamide prescribed?
Flutamide is used along with drugs such as leuprolide to treat prostate cancer. Flutamide belongs to a class of drugs known as antiandrogens. It blocks the effect of the male hormone testosterone. Giving Flutamide with leuprolide, which reduces the body’s testosterone levels, is one way of treating prostate cancer. For some forms of prostate cancer, radiation therapy is given along with the drugs.
Most important fact about Flutamide
Taking Flutamide and leuprolide together is essential in this form of treatment. You should not interrupt their doses or stop taking either of these medications without consulting your doctor.
How should you take Flutamide?
Take Flutamide exactly as prescribed. Do not use more or less, and do not take it more often than instructed.
If you develop diarrhea—a relatively common side effect of therapy—you may find the following measures helpful: drink plenty of fluids; avoid dairy products; increase your intake of whole grains, fruits, and vegetables; avoid laxatives; and take nonprescription antidiarrhea medicine. If the diarrhea continues or becomes severe, contact your doctor.
- If you miss a dose…Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at once.
- Storage instructions…Store at room temperature.
What side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor immediately. Since Flutamide is always given with another antiandrogen drug, when a side effect develops, it is difficult to know which drug is responsible. Only your doctor can determine if it is safe for you to continue taking Flutamide.
- Side effects may include: Breast tissue swelling and tenderness, diarrhea, hot flashes, impotence, loss of sex drive, nausea, vomiting
When the drugs are used along with radiation therapy, additional side effects may include bladder inflammation, bleeding from the rectum, blood in the urine, and intestinal problems.
Why should Flutamide not be prescribed?
This drug is not intended for women, and should not be used by anyone with serious liver disease. You’ll also be unable to take it if it gives you an allergic reaction.
Special warnings about Flutamide
Flutamide has been known to cause liver failure in some patients, in rare cases leading to death. Your doctor will do blood tests to check your liver function before you start treatment with Flutamide, and at regular intervals thereafter. If a liver problem does develop, you may need to take less Flutamide or stop taking the drug altogether. Report any signs or symptoms that might suggest liver damage to your doctor right away. Warning signs include dark urine, itching, flu-like symptoms, jaundice (a yellowing of the skin and eyes), persistent appetite loss, and persistent tenderness on the right side of the upper abdomen.
Possible food and drug interactions when taking Flutamide
If you are already taking the anticoagulant drug warfarin, you will need to be monitored especially closely after treatment with Flutamide begins. Your doctor may need to lower your dosage of warfarin.
Special information if you are pregnant or breastfeeding
Flutamide can harm a developing baby. Women should never take Flutamide, either during pregnancy or at any other time.
Recommended dosage for Flutamide
The recommended adult Flutamide dosage is 2 capsules 3 times a day at 8-hour intervals for a total daily dosage of 750 milligrams.
Over dosage
You may notice breast development or tenderness with an overdose of Flutamide. Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.
Related Links
| buyatrovent.com | buyflutamide.com | buybenzocaine.com |






